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LIV018

Development stage: Preclinical
Lead developer: Liveome
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics

Overview

LIV018 is an engineered live biotherapeutic product (eLBP) being developed by Liveome for the treatment of autoimmune diseases. As an eLBP, it consists of a live microorganism that has been genetically modified to enhance its therapeutic properties, such as the secretion of specific anti-inflammatory molecules or the modulation of the host immune system. The drug is currently in the discovery or preclinical stage of development, aiming to leverage the gut-immune axis to restore homeostasis in patients with various autoimmune conditions. It is distinguished from other candidates in Liveome's pipeline by its engineered modality specifically tailored for autoimmune indications.

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