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LIV019

Development stage: Preclinical
Lead developer: Liveome
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

LIV019 is an engineered live biotherapeutic product (eLBP) currently under development by Liveome for the treatment of hematologic cancers. As an eLBP, LIV019 consists of genetically modified bacteria designed to deliver therapeutic payloads or modulate the host's microbiome and immune system to target malignant cells. The product represents a novel approach in oncology, leveraging synthetic biology to create microbiome-based therapies with enhanced functionality compared to naturally occurring strains. It is currently in the discovery and preclinical stages of development.

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