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live attenuated varicella vaccine + live attenuated Japanese encephalitis vaccine
- Development stage
- Unknown
- Lead developer
- Merck
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Subcutaneous
01
Overview
This is a combination of two live attenuated vaccines administered together for the prevention of varicella (chickenpox) and Japanese encephalitis (JE). The live attenuated varicella vaccine contains an Oka strain of varicella-zoster virus, which induces immunity by mimicking natural infection and stimulating both humoral and cellular immune responses[1][5]. The live attenuated JE vaccine (such as JE-CV or SA14-14-2) uses a weakened form of the Japanese encephalitis virus to elicit protective neutralizing antibodies against JE[6][8]. Both vaccines are primarily indicated for children in endemic regions or travelers at risk. Co-administration has been shown to be safe and immunogenic, with no significant reduction in efficacy or increase in adverse events compared to separate administration[6][8].
- Other names
- Live Attenuated Varicella Vaccine + Live Attenuated JE VaccineVaricella and JE Vaccine Co-administration
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