Drug intelligence / Profile preview

Live Combined Bifidobacterium and Lactobacillus

Development stage: Unknown
Lead developer: First Affiliated Hospital of Xi'an Jiaotong University
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

Live Combined Bifidobacterium and Lactobacillus is a probiotic combination therapy containing live strains of *Bifidobacterium* and *Lactobacillus*. In the clinical context of the First Affiliated Hospital of Xi'an Jiaotong University, it is utilized as a standard 'basic treatment' protocol for patients with functional gastrointestinal disorders. The therapy works by colonizing the gastrointestinal tract to restore microbial balance, enhancing the intestinal mucosal barrier, and regulating gut motility and sensation. This specific oral formulation is used as a baseline comparator in studies evaluating the efficacy of advanced delivery methods, such as colonoscopic probiotic infusion, for treating functional constipation and irritable bowel syndrome (IBS).

Other names: Basic treatmentBasic treatment-First Affiliated Hospital Xi'an Jiaotong University-functional constipation-irritable bowel syndromeoral Live Combined Bifidobacterium and Lactobacillus tablets

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