Drug intelligence / Profile preview

live quadruple lactobacillus vaginal capsule

Development stage
Unknown
Lead developer
Shuangqi Pharmaceutical
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Vaginal
01

Overview

Live quadruple lactobacillus vaginal capsule is a live biotherapeutic product (LBP) containing four specific strains of beneficial bacteria: *Lactobacillus acidophilus*, *Lactobacillus casei*, *Lactobacillus rhamnosus*, and *Lactobacillus bulgaricus*. Developed and manufactured by Inner Mongolia Shuangqi Pharmaceutical, it is primarily indicated for the treatment of bacterial vaginosis and the restoration of vaginal microecology. The mechanism involves the colonization of the vaginal epithelium by these lactobacilli, which produce lactic acid and hydrogen peroxide to maintain a low vaginal pH (3.8–4.5), thereby inhibiting the overgrowth of anaerobic and pathogenic bacteria. Clinical trials are currently evaluating its safety and efficacy in postmenopausal atrophic vaginitis, a condition characterized by vaginal flora imbalance due to decreased estrogen levels.

Brand names
Yan Shuo延舒
Other names
阴道用乳杆菌四联活菌胶囊Yindao Yong Ruganjun Silian Huojun Jiaonang
02

Targets

BVAB (Bacterial vaginosis-associated bacteria)

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