Drug intelligence / Profile preview

lividomycin A

Development stage
Unknown
Lead developer
Streptomyces lividus
Modality
Small Molecules
01

Overview

Lividomycin A is a broad-spectrum aminoglycoside antibiotic produced by Streptomyces lividus. It is effective against most Gram-positive and Gram-negative bacteria, including Mycobacterium tuberculosis and Pseudomonas aeruginosa. The drug acts by binding to bacterial ribosomes and inhibiting protein synthesis, thereby exerting its antibacterial effects. Resistance to lividomycin develops more slowly in some bacteria compared to other aminoglycosides like kanamycin. It has shown efficacy in experimental infections with various bacteria, including strains resistant to other aminoglycosides[3][4][5].

Brand names
lividomycinLivodymycinLividomycineLividomicina
Other names
mannosyldeoxyparomomycinLividomycin [INN:DCF]Lividomycine [INN-French]Lividomycinum [INN-Latin]Lividomicina [INN-Spanish]
02

Targets

30S A-site (Bacterial ribosomal 30S A-site)

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