Drug intelligence / Profile preview

livionex

Development stage
Phase 1
Lead developer
Livionex
Modality
Small Molecules
Administration
Topical (oral/dental Gel), Topical (dermal Lotion Under Development), Ophthalmic (eye Drops)
01

Overview

Livionex is a proprietary formulation based on the active compound edathamil (EDTA), developed as a metal ion chelator for multiple therapeutic applications. Its mechanism centers on modulating metal ions involved in disease pathways—specifically targeting inflammation, biofilm formation, and lipid-protein aggregates. In oral care (as LIVFRESH/Livionex dental gel), it disrupts dental biofilm by chelating calcium within the plaque matrix to prevent its adhesion and maturation. In ophthalmology (as C-KAD eye drop), it is being developed as a 2.6% EDTA ophthalmic solution to treat early-to-moderate cataracts by penetrating the lens and reducing clouding through chelation of lens-bound metals that contribute to opacification. The technology platform has also been explored for dermatological uses such as treating lower leg edema and stasis dermatitis associated with chronic venous insufficiency[1][3][4][5][7][9].

Brand names
LivionexLIVFRESH
Other names
Livionex dental gelLivionex toothpasteC-KAD eye drop

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