Drug intelligence / Profile preview

Livionex CVI Topical Treatment

Development stage
Phase 1
Lead developer
Livionex
Modality
Small Molecules
Administration
Topical
01

Overview

Livionex CVI Topical Treatment is a topical pharmaceutical candidate developed by Livionex for the treatment of chronic venous insufficiency (CVI) and associated conditions, including stasis dermatitis, lower leg edema, and venous ulcers. The formulation utilizes a proprietary technology designed to target and modulate intracellular iron and calcium ions, which are key drivers of inflammation and blood pooling in the lower extremities. By addressing these ionic imbalances, the treatment aims to alleviate the underlying pathophysiology of CVI and promote healing of venous ulcers. It is currently undergoing Phase 1/2 clinical evaluation.

02

Targets

CA2 (Carbonic Anhydrase 2)Fe (Intracellular iron ions)

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