Drug intelligence / Profile preview

LiviUp

Development stage
Unknown
Lead developer
Entity Health
Modality
Small Molecules
Administration
Oral
01

Overview

LiviUp is a nutraceutical supplement developed by the Australian company Entity Health, designed to mitigate hangover symptoms and support liver detoxification. Its primary active ingredient is dihydromyricetin (DHM), a flavonoid extracted from *Hovenia dulcis* (Japanese Raisin Tree). LiviUp functions by modulating GABA (gamma-aminobutyric acid) neurotransmitter activity in the brain and enhancing the activity of key liver enzymes, specifically alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which accelerate the metabolism of alcohol and its toxic byproduct, acetaldehyde. It is marketed for the reduction of alcohol-related symptoms such as nausea, headache, and facial flushing. The product is manufactured in TGA and cGMP-compliant facilities in Victoria, Australia.

Brand names
LiviUp
02

Targets

GABA-B (Gamma-aminobutyric acid receptor type B)ALDH1A1 (Aldehyde dehydrogenase 1 family member A1)ADH (Alcohol dehydrogenase family)

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