Drug intelligence / Profile preview

LivRelief

Development stage
Unknown
Lead developer
Delivra
Modality
Small Molecules
Administration
Topical, Transdermal
01

Overview

LivRelief is a line of over-the-counter (OTC) topical pain relief creams developed by LivCorp Inc. (now part of Delivra Corp). The products are characterized by their use of the proprietary **Delivra** transdermal delivery system, which is designed to transport active ingredients through the skin to the underlying source of pain. The product line includes several specialized formulations: the Pain Relief and Extra Strength Nerve Pain Relief creams utilize capsaicin to target pain receptors and reduce inflammation; the Original Pain Relief Cream contains rutin, a bioflavonoid with antioxidant properties; the Varicose Vein Cream contains witch hazel; and the Healing Cream uses calendula for wound recovery. These products are indicated for a variety of conditions including muscle and joint pain, osteoarthritis, rheumatoid arthritis, shingles, diabetic neuropathy, and sciatica.

Brand names
LivRelief
02

Targets

TRPV1 (Transient receptor potential cation channel subfamily V member 1)MPO (Myeloperoxidase)PHB2 (Prohibitin 2)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)CYP3A4 (Cytochrome P450 3A4)

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