Drug intelligence / Profile preview

Lixuesheng + Bolten

Development stage
Unknown
Lead developer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Modality
Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Lixuesheng + Bolten is a combination therapy comprising a plant extract complex (Lixuesheng) and a whey-derived lactoferrin supplement (Bolten). Lixuesheng is a name traditionally associated with hematopoietic stimulants in China, used to treat leukopenia and promote the recovery of white blood cell counts; in this specific formulation, it is described as a botanical complex. Bolten is a brand of whey lactoferrin, a multifunctional protein with immunomodulatory, anti-inflammatory, and iron-binding properties. This combination is currently being investigated in Phase II clinical trials (e.g., ChiCTR2000039302) for its potential to mitigate chemotherapy-induced myelosuppression in patients with lung cancer. The study aims to determine if the synergistic effects of these components can improve hematological parameters, reduce the incidence of infections, and enhance the overall quality of life for patients undergoing cytotoxic chemotherapy.

Brand names
LixueshengBolten
Other names
Lixuesheng plant extract complex + Bolten whey lactoferrin capsule
02

Targets

ITLN1 (Intelectin-1)LRP1 (Prolow-density lipoprotein receptor-related protein 1)

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