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Lizhong Fuyuan Recipe

Development stage: Preclinical
Lead developer: Shanghai Municipal Hospital of Traditional Chinese Medicine
Modality: Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration: Oral

Overview

Lizhong Fuyuan Recipe is a traditional Chinese medicine (TCM) herbal formula used primarily for the treatment of chronic atrophic gastritis with spleen deficiency and phlegm stasis. It is based on classical TCM principles aimed at warming and reinforcing the spleen and stomach, dispelling cold, resolving phlegm, and promoting blood circulation. The formula is typically composed of multiple herbs; while the exact composition for "Lizhong Fuyuan Recipe" may vary by practitioner or study, it is related to or derived from classic formulas such as Lizhong Pill (which contains Panax ginseng, Zingiber officinale [ginger], Atractylodes macrocephala, Glycyrrhiza uralensis [licorice]) and may include additional herbs to address specific TCM patterns like blood stasis or phlegm retention[2][1]. Mechanistically, studies suggest that similar formulas can modulate neuroendocrine-immune function in animal models of spleen deficiency by regulating cytokines such as IL-1, IL-6, TNF-α, IFN-γ as well as gastrointestinal hormones like gastrin[2]. Clinical use focuses on improving digestive symptoms associated with chronic gastritis within a TCM diagnostic framework.

Other names: Lizhong Fuyuan Fang理中复元方

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