Drug intelligence / Profile preview

LLK203

Development stage
Preclinical
Lead developer
China Pharmaceutical University
01

Overview

LLK203: sourced facts only. name: "These results underscore the potential of LLK203 as a promising dual-target inhibitor of USP2/USP8 for breast cancer treatment." [PMID:38452725]; target: "These results underscore the potential of LLK203 as a promising dual-target inhibitor of USP2/USP8 for breast cancer treatment." [PMID:38452725]; target: "These results underscore the potential of LLK203 as a promising dual-target inhibitor of USP2/USP8 for breast cancer treatment." [PMID:38452725]; developer: "Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, PR China." [PMID:38452725]; stage: "Moreover, LLK203 exhibited potent in vivo efficacy in the 4T1 homograft model, while maintaining a low toxicity profile." [PMID:38452725]

02

Targets

USP2 (Ubiquitin-specific peptidase 2)USP8 (Ubiquitin-specific protease 8)

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