Drug intelligence / Profile preview

LMR Plus

Development stage
Approved
Lead developer
V2 Pharma
Modality
Small Molecules
Administration
Topical
01

Overview

LMR Plus is a **topical combination analgesic/anesthetic kit** marketed by V2 Pharma that contains **lidocaine** and **menthol** as active ingredients, including a **lidocaine patch 5%** component. It is used primarily for topical pain relief, especially pain associated with **post-herpetic neuralgia**, and has also been associated in source context with broader minor musculoskeletal and neuropathic pain uses typical of lidocaine and menthol topical products. Mechanistically, lidocaine is a small-molecule **local anesthetic** that reduces pain signaling by blocking voltage-gated sodium channels in peripheral nerves, while menthol provides cooling or warming counterirritant effects via thermosensory signaling that helps modulate local pain perception. The available source text indicates this product is marketed but also notes that its labeling states it has **not been found by FDA to be safe and effective and has not been approved by FDA**.

Brand names
LMR Plus
Other names
lidocaine + menthol topical kitlidocaine patch 5% + menthol
02

Targets

TRPM8 (Transient receptor potential cation channel subfamily M member 8)NaV (Voltage-gated sodium channels)

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