Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
LNTH-1363S
- Development stage
- Unknown
- Lead developer
- Lantheus
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
LNTH-1363S is a fibroblast activation protein (FAP) inhibitor radiodiagnostic agent developed for positron emission tomography (PET) imaging. It is a trifunctional small molecule that binds with high affinity to FAP and is radiolabeled with copper-64 (^64Cu), enabling PET imaging of tumors and fibrotic tissues where FAP is overexpressed. The compound has demonstrated favorable safety and biodistribution in first-in-human studies, with primary excretion via the kidneys and minimal off-target uptake. Its main application is in oncology for imaging various cancers including sarcoma and gastrointestinal tract cancers[1][2][5].
- Other names
- 64Cu-LNTH-1363SRTX-1363SRTX1363SRTX 1363SFAP-Dx
02
Targets
FAP (Fibroblast activation protein alpha)
Beyond the preview
Go deeper on LNTH-1363S.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on LNTH-1363S.