Drug intelligence / Profile preview

LO2A

Development stage
Unknown
Lead developer
Kosmos
Modality
Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Administration
Ophthalmic
01

Overview

**LO2A** is a preservative-free, unit-dose ophthalmic lubricant formulation developed for dry-eye disease. Its principal therapeutic component is sodium hyaluronate, a viscoelastic, water-retaining polymer that supplements and stabilizes the tear film and provides ocular-surface lubrication; the formulation also contains glycerol and carbomer as excipients. LO2A has been studied in randomized trials for moderate-to-severe conjunctivochalasis and for dry eye associated with Sjögren's syndrome. Resdevco developed and owned the intellectual property, while Wize Pharma and its subsidiary OcuWize licensed and clinically developed/commercialized rights in selected territories. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03319420))

Brand names
LacryconConhealEyeconHylanDropyalXidan
Other names
L02AL-02AL 02A

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