Drug intelligence / Profile preview

lobaplatin + nab-paclitaxel + tislelizumab

Development stage
Preclinical
Lead developer
BeiGene
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration
Intravenous
01

Overview

This is a combination therapy consisting of three distinct agents:\n\n**Tislelizumab** is a monoclonal antibody that targets PD-1 (programmed death receptor 1). It blocks the interaction between PD-1 and its ligands (PD-L1/PD-L2), preventing cancer cells from evading immune detection. Unlike some other PD-1 inhibitors, tislelizumab is specifically engineered to minimize binding to FcγR on macrophages, which reduces antibody-dependent phagocytosis and potentially improves efficacy. By blocking the PD-1/PD-L1 pathway, tislelizumab restores T-cell function through enhanced cytokine production, resulting in immune-mediated antitumor activity.\n\n**Lobaplatin** is a platinum-based chemotherapeutic agent.\n\n**Nab-paclitaxel** (albumin-bound paclitaxel) is a taxane chemotherapy that inhibits cell division by stabilizing microtubules.\n\nThis triple combination likely aims to leverage both immunotherapy and chemotherapy mechanisms for enhanced anticancer effects.

02

Targets

MicrotubuleDNAPDCD1 (Programmed cell death protein 1 receptor)

Beyond the preview

Go deeper on lobaplatin + nab-paclitaxel + tislelizumab.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on lobaplatin + nab-paclitaxel + tislelizumab.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call