Drug intelligence / Profile preview

lolium perenne + cynodon dactylon

Development stage
Phase 2
Lead developer
Leti Pharma
Administration
Sublingual
01

Overview

Lolium perenne + cynodon dactylon is a combination allergenic extract used in allergen-specific immunotherapy (AIT). Developed by Laboratorios Leti, it consists of depigmented and polymerized pollen extracts from Perennial Ryegrass (*Lolium perenne*) and Bermuda Grass (*Cynodon dactylon*). This formulation is designed for sublingual administration to treat patients with allergic rhinoconjunctivitis. The depigmentation and polymerization process is intended to reduce the allergenicity (IgE binding) of the extract, thereby improving safety and allowing for higher doses, while maintaining or enhancing its immunogenicity (the ability to induce a protective immune response).

Brand names
SublivacDepigoid
Other names
lolium perenne and cynodon dactylon pollen extractperennial ryegrass and bermuda grass extractgrass pollen allergenic extract (L. perenne-C. dactylon)depigmented and polymerized grass pollen extract
02

Targets

Phleum pratense allergens

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