Drug intelligence / Profile preview

Londar

Development stage
Unknown
Lead developer
Bruno Farmaceutici
Modality
Small Molecules
Administration
Oral
01

Overview

**Londar** is an oral fixed-dose antihypertensive combination marketed by Bruno Farmaceutici in Italy. It contains candesartan cilexetil, an angiotensin II type 1 receptor blocker; amlodipine, an L-type calcium-channel blocker; and hydrochlorothiazide, a thiazide diuretic that inhibits the renal sodium-chloride symporter. It is authorized for substitution treatment of essential hypertension in adults whose blood pressure is already adequately controlled with the three components given concurrently at the same doses.

Brand names
Londar
Other names
amlodipine + candesartan cilexetil + hydrochlorothiazidecandesartan + amlodipine + hydrochlorothiazidecandesartan cilexetil + amlodipina + idroclorotiazide
02

Targets

AGTR1 (Angiotensin II Type-1 receptor)LTCC (Voltage-gated calcium channel (L-type))SLC12A3 (Thiazide-sensitive sodium-chloride cotransporter)

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