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Lonicerae japonicae flos refers to the dried flower buds or flowers of *Lonicera japonica* Thunb., commonly known as Japanese honeysuckle. It is a major traditional Chinese medicine (TCM) herb with a long history of use for "clearing heat and detoxifying" in TCM theory. Modern pharmacological research has identified over 500 compounds in LJF, including flavonoids (such as luteolin and rutin), organic acids (notably chlorogenic acid), iridoids, triterpenes, and volatile oils[2][3]. These constituents contribute to its broad range of biological activities: - Antioxidant - Anti-inflammatory - Antibacterial - Antiviral - Immunomodulatory - Potential anticancer effects[2][6] Clinically and traditionally, it is used for conditions such as fever, sore throat, upper respiratory tract infections (including colds and flu), skin infections/ulcers/rashes/carbuncles with pus or swelling ("toxic heat"), digestive disorders like enteritis and dysentery, arthritis, diabetes management support, urinary disorders, headaches/fever reduction ("cooling" effect), liver protection and cardiovascular health[1][4][5][6]. In vitro studies suggest mechanisms may include cell cycle arrest in cancer cells via downregulation of CDC25A or induction of reactive oxygen species by certain flavonoids[2]. It is widely consumed both medicinally (as decoctions/teas/tinctures) and as a functional food ingredient.
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