Drug intelligence / Profile preview

loratadine + mometasone furoate

Development stage
Unknown
Lead developer
Merck
Modality
Small Molecules
Administration
Intranasal, Oral
01

Overview

Loratadine + mometasone furoate is a combination therapy used for the treatment of allergic rhinitis. This combination pairs loratadine, a non-sedating antihistamine, with mometasone furoate, an intranasal corticosteroid. Loratadine works by blocking histamine receptors, while mometasone furoate reduces inflammation in the nasal passages. Clinical studies have shown that this combination provides similar benefits to mometasone furoate monotherapy for treating seasonal allergic rhinitis symptoms.

02

Targets

GR (Glucocorticoid receptor)HRH1 (Histamine H1 Receptor)

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