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lorazepam + placebo
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Oral, Intravenous, Intramuscular, Transdermal
01
Overview
Lorazepam is a benzodiazepine medication used primarily to relieve anxiety, treat insomnia related to anxiety or situational stress, control agitation caused by alcohol withdrawal, and manage nausea and vomiting from cancer treatment. It works by enhancing the activity of gamma-aminobutyric acid (GABA), a calming neurotransmitter in the brain, thereby slowing brain activity to produce relaxation. Placebo is an inert substance with no pharmacological effect used as a control in clinical trials. The combination "placebo + lorazepam" typically refers to clinical trial settings where one group receives lorazepam and another receives placebo for comparison purposes; it is not a marketed drug product but rather denotes the presence of both active drug and placebo arms in studies. Lorazepam can be administered orally (tablet, extended-release capsule, liquid concentrate), intravenously, intramuscularly, or transdermally depending on indication[1][2][3][4][5].
- Brand names
- Ativan
- Other names
- placebo + lorazepam
02
Targets
GABAA (Gamma-aminobutyric acid receptor)
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