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Lost Mary
- Development stage
- Unknown
- Lead developer
- iMiracle Technology
- Modality
- Small Molecules, Device-based Delivery → Drug Delivery Systems
- Administration
- Inhalation
01
Overview
Lost Mary is a brand of disposable electronic nicotine delivery systems (ENDS) developed by Shenzhen iMiracle Technology. The products function by heating a nicotine-containing e-liquid solution to create an aerosol for inhalation. The primary active constituent is nicotine, typically in the form of nicotine salts, which acts as an agonist at nicotinic acetylcholine receptors (nAChRs) throughout the peripheral and central nervous systems. This binding triggers the release of several neurotransmitters, including dopamine, norepinephrine, and acetylcholine, mediating the reinforcing effects and physiological stimulation associated with use. While primarily marketed for recreational use and as a harm-reduction alternative to combustible tobacco, the device serves as a delivery vehicle for the pharmacological agent nicotine.
- Brand names
- Lost Mary
- Other names
- Lost Mary OS5000Lost Mary BM600Lost Mary MO5000Lost Mary Vape
02
Targets
α4β2 nAChR (Nicotinic acetylcholine receptor alpha4 beta2 subtype)
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