Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
low anticoagulant bovine heparin
- Development stage
- Preclinical
- Lead developer
- Federal University of Rio de Janeiro
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Low anticoagulant bovine heparin (LABH) is a purified fraction of bovine unfractionated heparin (UFH) characterized by significantly reduced anticoagulant activity (~20 IU/mg) compared to standard porcine or bovine UFH. Developed by researchers at the Universidade Federal do Rio de Janeiro, LABH is being investigated for its antimetastatic properties. Its primary mechanism involves disrupting the interaction between circulating tumor cells and platelets by inhibiting P-selectin binding. By blocking these interactions, LABH aims to prevent the formation of metastatic foci in the bloodstream while minimizing the risk of bleeding side effects typically associated with therapeutic doses of standard heparin.
- Other names
- low anticoagulant bovine heparin
02
Targets
ATIII (Antithrombin III)F2 (Thrombin)SELL (L-selectin)F10 (Factor Xa)SELP (P-selectin)PF4 (Platelet factor 4)
Beyond the preview
Go deeper on low anticoagulant bovine heparin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on low anticoagulant bovine heparin.