Low-dose vaginal estrogen in Vanicream Lite

Low-dose vaginal estrogen in Vanicream Lite refers to a specific compounded formulation of either 10 micrograms of estriol or 10 micrograms of estradiol valerate in 0.5 grams of Vanicream Lite base. Developed for a Phase 3 randomized controlled trial led by Maire Mac Bride at the Mayo Clinic, these formulations are intended for the treatment of atrophic vaginitis in postmenopausal women. The treatment strategy utilizes a dose significantly lower (one-tenth) than standard commercial preparations and employs application to the vaginal introitus to provide local symptomatic relief while minimizing systemic estrogen exposure and potential side effects.

Other names

Estriol 10 mcg in Vanicream LiteEstriol10 mcg in Vanicream LiteEstriol-10 mcg in Vanicream LiteEstradiol valerate 10 mcg in Vanicream LiteLow Dose Vaginal Estrogens for Atrophic Vaginitis