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LP-DF003 is a small molecule drug developed by Mireca Medicines GmbH (formerly 2-BBB Medicines BV) for the treatment of inherited retina degeneration, including retinitis pigmentosa. The drug functions by down-regulating overexpressed cyclic guanosine monophosphate (cGMP). It has received EMA Orphan Drug Status for retinitis pigmentosa and has completed pharmacological proof-of-concept studies.
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