Drug intelligence / Profile preview

LP0113

Development stage
Unknown
Lead developer
LEO Pharma
Modality
Small Molecules
Administration
Topical
01

Overview

**LP0113** was an investigational topical fixed-dose aerosol spray developed by LEO Pharma for psoriasis vulgaris. It combined calcipotriol, a vitamin D receptor agonist, with betamethasone dipropionate, a glucocorticoid receptor agonist, to reduce psoriatic inflammation and abnormal keratinocyte proliferation. In the completed Phase 2a LP0113-1123 plaque-test study, LP0113 was evaluated against vehicle, the individual active ingredients in the same spray vehicle, Daivobet gel, and LEO 90100 aerosol foam; LP0113 is therefore distinct from the comparator product LEO 90100. ([cdek.pharmacy.purdue.edu](https://cdek.pharmacy.purdue.edu/trial/NCT02416258/))

Other names
LP0113 aerosol sprayLP-0113 aerosol sprayLP 0113 aerosol spray
02

Targets

GR (Glucocorticoid receptor)VDR (Vitamin D receptor)

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