Drug intelligence / Profile preview

LPH-1xx

Development stage: Preclinical
Lead developer: Lophora
Modality: Small Molecules
Administration: Oral

Overview

LPH-1xx is a preclinical-stage, selective small-molecule agonist of the serotonin 5-HT2A receptor (5-HT2AR) being developed by Lophora. Originating from Lophora's drug discovery platform, which focuses on the rational engineering of selective 5-HT2A agonists with optimized drug-like properties, LPH-1xx is designed to target central nervous system (CNS) disorders. The compound is currently in preclinical development for the treatment of neurodegenerative diseases and substance abuse.

Targets

HTR2A (Serotonin receptor 5-HT2A)

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