LS-002

LS-002 is a long-acting injectable formulation of the analgesic buprenorphine, developed by Lifescient for the management of pain in dogs. The product utilizes Lifescient's proprietary "Life-Sustained" (LS) technology, which is a lipid-based delivery system designed to provide sustained release of the active ingredient over several days from a single administration. Buprenorphine is a potent opioid that acts as a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor, providing effective analgesia with a wider safety margin than full mu-agonists. LS-002 is intended to provide consistent, multi-day pain control in canine patients, particularly following surgical procedures, thereby improving clinical compliance and reducing the need for frequent redosing in veterinary settings.