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LS-05 is a preclinical-stage chimeric antigen receptor (CAR) T-cell therapy being developed by LentiStem Biotech, a Spanish biotechnology company specializing in lentiviral vector-based therapies. The candidate is designed to treat solid tumors and leverages the company's proprietary Lent-On-Plus platform, which aims to enhance the safety and efficacy of CAR-T cells by providing controlled transgene expression. As of 2024, the specific biological target of LS-05 has not been publicly disclosed, and the program is in the early proof-of-concept or preclinical stage of development.
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