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LSD1-UM-109
- Development stage
- Preclinical
- Lead developer
- University of Michigan
01
Overview
LSD1-UM-109: sourced facts only. name: "Among them, 46 shows an IC50 value of 3.1 nM in inhibition of LSD1 enzymatic activity and inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line." [PMID:37849536]; target: "Among them, 46 shows an IC50 value of 3.1 nM in inhibition of LSD1 enzymatic activity and inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line." [PMID:37849536]; developer: "Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States." [PMID:37849536]; stage: "Among them, 46 shows an IC50 value of 3.1 nM in inhibition of LSD1 enzymatic activity and inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line." [PMID:37849536]
02
Targets
KDM1A (LSD1)
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