Drug intelligence / Profile preview

LSPN925

Development stage
Preclinical
Modality
Small Molecules
01

Overview

LSPN925 is an experimental **coumarin-dihydropyrimidinone hybrid** small molecule reported in a 2025 medicinal chemistry study as an in vitro anticancer lead for ovarian cancer research. In that publication, it emerged as one of the more active synthesized compounds in a panel of cancer cell assays and was further evaluated for effects on cell morphology and colony formation. Its precise validated molecular target and mechanism of action were not disclosed in the provided source, so it is best described at present as a preclinical cytotoxic antineoplastic research compound rather than a clinically developed drug candidate.

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