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LTI-003 is a preclinical-stage recombinant protein-based immunotherapy being developed by Leukogene Therapeutics for the treatment of hematologic malignancies. It is built on the company's proprietary M2T™ (MHC class II-Targeting) platform, which utilizes MHC class II-engaging technology to redirect the immune system against cancer cells. While the specific molecular target remains undisclosed, the drug functions as an MHC class II engager, a modality designed to activate and recruit immune effector cells to the tumor microenvironment. The asset is currently positioned in the discovery and preclinical stages of development for heme oncology indications.
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