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LU AA34893 is an investigational small molecule antidepressant developed by Lundbeck for the oral treatment of major depressive disorder and bipolar depression. It acts as a serotonin receptor modulator, affecting several monoaminergic systems with allosteric effects. Preclinical studies suggested superior antidepressant efficacy compared to existing treatments, but clinical development was discontinued after Phase 2 trials for both major depressive disorder and bipolar disorders[1][2][3][6].
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