Drug intelligence / Profile preview

Lumet HS

Development stage
Unknown
Lead developer
Quality Chemical Industries
Modality
Small Molecules
Administration
Oral
01

Overview

Lumet HS is a fixed-dose combination antimalarial drug developed and manufactured by Quality Chemicals Industries Limited (QCIL) in Uganda. It is a higher-dose formulation containing 80 mg of artemether and 480 mg of lumefantrine in a single oral tablet, designed for adults and children weighing over 35 kg. Artemether, an artemisinin derivative, provides a rapid onset of action by interfering with heme metabolism and damaging parasite biomolecules, leading to quick symptomatic relief. Lumefantrine acts as a long-acting blood schizonticide that clears residual parasites to prevent recrudescence. This combination therapy is indicated for the treatment of uncomplicated malaria caused by *Plasmodium falciparum* and other *Plasmodium* species, and is particularly effective against chloroquine-resistant strains.

Brand names
Lumet HSLumet HS 80
Other names
artemether + lumefantrineAL
02

Targets

β-Hematin

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