Drug intelligence / Profile preview

Lunalbell ULD

Development stage
Phase 3
Lead developer
Nobelpharma
Modality
Small Molecules
Administration
Oral
01

Overview

NPC-01 (Lunalbell ULD) is an ultra-low-dose oral combination drug containing 1 mg of norethisterone and 0.02 mg of ethinyl estradiol. Developed by Nobelpharma, it is specifically indicated for the treatment of dysmenorrhea associated with endometriosis or functional dysmenorrhea. As a combination hormonal contraceptive, it works by binding to and activating progesterone and estrogen receptors, which leads to the suppression of gonadotropins (FSH and LH), inhibition of ovulation, and alteration of the endometrium to reduce menstrual pain and volume. Clinical studies have shown that this ultra-low-dose formulation provides efficacy in pain relief comparable to standard low-dose formulations while minimizing estrogen-related side effects.

Brand names
Lunalbell
Other names
norethisterone + ethinyl estradiolnorethisterone 1mg + ethinyl estradiol 0.02mg
02

Targets

PR (Progesterone receptor)ESR1 (ERα)PGRMC1ESR2 (ERβ)AR (Adrenergic receptors)

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