Drug intelligence / Profile preview

Luofushan Baicao Oil

Development stage
Preclinical
Lead developer
Jiangxi Baicao Pharmaceutical
Modality
Small Molecules
Administration
Topical, Inhalation
01

Overview

Luofushan Baicao Oil is an essential oil-rich traditional Chinese medicine (TCM) formula composed of extracts from seventy-nine botanical drugs. It is commonly used for the relief of cold symptoms, headache, insect bites, and swelling. Pharmacological studies indicate that it inhibits the proliferation of influenza A virus (H1N1), reduces viral titers in cell models, and decreases inflammatory cytokines such as IL-1β and IL-6. In animal models, inhalation of its aerosol reduced lung damage caused by viral infection. Mechanistically, it acts as an inhibitor of the TLR3/NF-κB signaling pathway and modulates immune responses by downregulating NF-κB p65 and IRF3 expression[2][3][4]. It is considered a substitute medicinal agent for prevention of influenza.

Brand names
Luofushan Baicao Oil
Other names
LBOLuofushan-Baicao Oil
02

Targets

IRF3 (Interferon regulatory factor 3)TLR3 (Toll-like receptor 3)NF-κB

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