luprostiol

Luprostiol is a synthetic analogue of prostaglandin F2α, classified as a luteolytic agent. Its primary mechanism of action is to induce luteal regression in animals with an active corpus luteum, leading to subsequent follicle growth, estrus, and ovulation. It is used primarily in veterinary medicine for estrus control and termination of pregnancy in mares and cattle. Luprostiol acts by mimicking the effects of endogenous prostaglandin F2α on the corpus luteum, resulting in its breakdown (luteolysis). The drug is rapidly absorbed after intramuscular injection and metabolized quickly. It has been formulated as an injectable solution (typically 7.5 mg/mL) and has been available for veterinary use in Europe for several years[3][5][6][8].

Brand names

LuprostiolR

Other names

Luprostiolum