Drug intelligence / Profile preview

LVK201

Development stage
Preclinical
Lead developer
Laverock Therapeutics
Modality
RNA Therapeutics → Nucleic Acid Therapeutics, CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

LVK201 is an ex vivo engineered CAR-T cell therapy being developed by Laverock Therapeutics for the treatment of solid tumors. The therapy is built on Laverock's proprietary GEiPS (Gene Editing induced Gene Silencing) platform, which utilizes programmable gene silencing via recoded microRNAs (miRNAs) to modulate gene expression within the therapeutic cells. This approach is designed to enhance the efficacy, persistence, and performance of CAR-T cells, particularly in overcoming the immunosuppressive microenvironment characteristic of solid tumors. As of early 2024, LVK201 is in the preclinical research stage and is subject to active partnering discussions.

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