Drug intelligence / Profile preview

LX12002

Development stage
Preclinical
Lead developer
Loxagen
Modality
Small Molecules
01

Overview

LX12002 is a preclinical-stage small molecule inhibitor of arachidonate 12-lipoxygenase (ALOX12, also known as 12LOX) being developed by Loxagen. The drug is designed to treat heparin-induced thrombocytopenia (HIT) by selectively inhibiting ALOX12, which is intended to reduce thrombosis without increasing the risk of bleeding. LX12002 is currently in the lead optimization stage of preclinical development.

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