Drug intelligence / Profile preview

LY231514 tetra glu

Development stage
Unknown
Lead developer
Eli Lilly
Modality
Small Molecules
01

Overview

LY231514 tetra glu is an experimental small molecule drug belonging to the class of pentacarboxylic acids and derivatives. It has been studied as a potential anticancer agent. Its primary mechanism of action is inhibition of thymidylate synthase (in yeast), an enzyme critical for DNA synthesis and repair, making it a candidate for antineoplastic therapy. The compound has not received regulatory approval in the US or elsewhere and does not have any approved indications. There are no reported clinical trials beyond preclinical or discovery phases[1][4].

02

Targets

TS (Thymidylate synthase)

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