Drug intelligence / Profile preview

LY900021

Development stage
Unknown
Lead developer
Eli Lilly
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Subcutaneous
01

Overview

**LY900021** was an investigational subcutaneous formulation of **mirikizumab** developed by Eli Lilly. It combined mirikizumab, a humanized IgG4 monoclonal antibody against the p19 subunit of interleukin-23, with LY9999QS, a permeation enhancer intended to improve the tolerability and administration of larger-volume subcutaneous injections. The formulation was evaluated in completed Phase 1 healthy-volunteer studies and has not been established as a marketed product.

Other names
LY 900021LY900021LY-900021LY9999QS + mirikizumab
02

Targets

IL23A (Interleukin-23 p19 Subunit)

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