Drug intelligence / Profile preview

lycium barbarum

Development stage
Preclinical
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Lycium barbarum is a deciduous shrub native to East Asia whose bright red berries are widely known as goji berries or gou qi zi (枸杞子) in Traditional Chinese Medicine (TCM). The dried fruit is used both as a food and medicinal herb. Lycium barbarum contains bioactive compounds such as polysaccharides, carotenoids (notably zeaxanthin), flavonoids, vitamins A and C, and minerals. Traditionally regarded as a tonic for the liver and kidneys in TCM, it is used to nourish yin and blood, improve vision (especially night vision), support immune function, promote longevity and vitality, enhance sexual function/fertility, moisten the lungs for dry coughs, replenish qi and blood deficiencies, brighten eyesight due to liver/kidney deficiency syndromes in TCM theory[5][7][10]. Modern research supports its antioxidant activity; immunomodulatory effects; neuroprotective properties; hepatoprotective actions; anti-inflammatory effects; adaptogenic qualities for stress resistance; metabolic regulation including glycemic control; cardiovascular benefits; prebiotic activity on gut flora[1][5][8]. Clinical studies suggest potential benefits for eye health (macular pigment density/zeaxanthin content), immune modulation/inflammation reduction/cancer prevention adjuncts/metabolic syndrome management/liver protection/anti-aging[1][8]. It is generally considered safe but may interact with certain medications metabolized by cytochrome P450 enzymes.

Other names
goji berrygou qi ziChinese wolfberrylycii berry枸杞子
02

Targets

PRR (Pattern recognition receptors)

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