Drug intelligence / Profile preview

lycium barbarum juice

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Lycium barbarum juice is a dietary supplement derived from the berries of the Lycium barbarum plant, commonly known as goji berry or wolfberry. Traditionally used in Asian medicine for various health conditions including poor vision, anemia, inflammation, and cough[5][6], it is now marketed globally as a "superfood" due to its high antioxidant content. The primary bioactive components are polysaccharides and carotenoids (notably zeaxanthin), which are thought to contribute to its purported antioxidant and immune-modulating effects[1][2][5]. Preclinical studies suggest potential benefits such as antitumor activity (via immune enhancement and apoptosis induction), hepatoprotection (possibly through PI3K/AKT/Nrf2 pathway activation), neuroprotection, improved glucose regulation, and protection against oxidative stress[2][5][7]. However, clinical evidence supporting these claims remains limited; most human data come from small or low-quality trials showing improvements in subjective well-being or biomarkers of oxidative stress rather than hard clinical outcomes[1][3][7]. Lycium barbarum juice may interact with certain medications—most notably warfarin—by increasing bleeding risk due to CYP enzyme inhibition[4][5].

Other names
goji juicewolfberry juicegou qi zi juiceLycium fruit juiceChinese wolfberry juice

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