Drug intelligence / Profile preview

lycopene phytosterol ester

Development stage
Unknown
Lead developer
HSF Biotech
Modality
Small Molecules, Inhalation Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Lycopene phytosterol ester is a combination dietary supplement ingredient composed of lycopene, a carotenoid antioxidant found in red fruits and vegetables, and phytosterol esters, which are plant-derived sterols chemically bonded to fatty acids. Lycopene acts as an antioxidant that may help protect cells from oxidative damage and has been studied for potential benefits in reducing the risk of certain cancers (notably prostate cancer) and cardiovascular disease[2]. Phytosterol esters are used primarily for their cholesterol-lowering effects; they reduce intestinal absorption of cholesterol by competing with dietary and biliary cholesterol for incorporation into micelles, leading to decreased serum LDL-cholesterol levels[1][3][4][5]. Esterification increases the lipid solubility of phytosterols, allowing them to be incorporated into fat-containing foods or supplements more efficiently[5][6]. This combination is marketed as a functional food ingredient or supplement aimed at supporting cardiovascular health by lowering LDL-cholesterol while providing antioxidant support.

02

Targets

NPC1L1 (Niemann-pick C1-Like 1 transporter)

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