Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
LYN-057
- Development stage
- Unknown
- Lead developer
- Lyndra Therapeutics
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
LYN-057 is an investigational, orally administered, once-weekly gastro-retentive extended-release formulation of memantine hydrochloride, developed by Lyndra Therapeutics for the treatment of Alzheimer's disease. The drug utilizes Lyndra's proprietary stellate (star-shaped) delivery platform, which consists of a capsule containing polymer-coated drug-loaded arms that unfold in the stomach. This design allows the dosage form to be retained in the stomach for approximately one week, providing sustained release of memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist. By reducing dosing frequency from daily to once weekly, LYN-057 aims to improve medication adherence in patients with Alzheimer's disease.
- Other names
- memantine HCl extended releaseonce-weekly memantine
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)
Beyond the preview
Go deeper on LYN-057.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on LYN-057.