Drug intelligence / Profile preview

lyophilized black raspberry

Development stage
Unknown
Lead developer
The Ohio State University Comprehensive Cancer Center - James Cancer Hospital
Modality
Small Molecules
Administration
Oral
01

Overview

A lyophilized (freeze-dried) black raspberry functional food product developed by the Ohio State University Comprehensive Cancer Center for cancer prevention research, specifically in patients with prostate cancer. The intervention delivers concentrated phytochemicals, including anthocyanins (such as cyanidin-3-rutinoside) and ellagitannins, which are metabolized into bioactive compounds like protocatechuic acid and urolithin A. It is administered in formulations such as gummy confections or nectar. The product aims to modulate biological pathways involved in cancer progression, including lowering insulin-like growth factor-I (IGF-I) and androgen levels, while increasing IGF-binding protein 3 (IGF-BP3) and exerting anti-inflammatory and antioxidant effects.

Other names
black raspberry bioactive compoundslyophilized black raspberry confectionblack raspberry nectarblack raspberry gummy confections
02

Targets

IGFBP3 (Insulin-like growth factor-binding protein 3)IGF-1R (Insulin-like growth factor 1 receptor)

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