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lyophilized black raspberry
- Development stage
- Unknown
- Lead developer
- The Ohio State University Comprehensive Cancer Center - James Cancer Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A lyophilized (freeze-dried) black raspberry functional food product developed by the Ohio State University Comprehensive Cancer Center for cancer prevention research, specifically in patients with prostate cancer. The intervention delivers concentrated phytochemicals, including anthocyanins (such as cyanidin-3-rutinoside) and ellagitannins, which are metabolized into bioactive compounds like protocatechuic acid and urolithin A. It is administered in formulations such as gummy confections or nectar. The product aims to modulate biological pathways involved in cancer progression, including lowering insulin-like growth factor-I (IGF-I) and androgen levels, while increasing IGF-binding protein 3 (IGF-BP3) and exerting anti-inflammatory and antioxidant effects.
- Other names
- black raspberry bioactive compoundslyophilized black raspberry confectionblack raspberry nectarblack raspberry gummy confections
02
Targets
AR (Adrenergic receptors)IGF-1 (Insulin-like growth factor 1)IGFBP3 (Insulin-like growth factor-binding protein 3)
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