Drug intelligence / Profile preview

lysine acetylsalicylate

Development stage
Phase 4
Lead developer
Bayer
Modality
Small Molecules
Administration
Oral, Intravenous, Intramuscular
01

Overview

**Aspisol** is a Bayer brand of **lysine acetylsalicylate**, specifically DL-lysine monoacetylsalicylate, a water-soluble lysine salt of acetylsalicylic acid. It is an injectable salicylate nonsteroidal anti-inflammatory drug with analgesic, antipyretic, anti-inflammatory, and antiplatelet activity. The acetylsalicylate moiety irreversibly inhibits cyclooxygenase enzymes, reducing prostaglandin synthesis and platelet thromboxane A2 generation. Historical product information describes Aspisol as powder with solvent for preparation of an injection or infusion solution, used for acute pain, fever requiring rapid reduction, rheumatic disorders, superficial thrombophlebitis, and postoperative thrombosis and embolism prophylaxis. ([klinikum.uni-heidelberg.de](https://www.klinikum.uni-heidelberg.de/fileadmin/medizinische_klinik/Abteilung_3/pdf/ivandic/FI_aspisol.pdf))

Brand names
AcelysinAspegicAspidolAspisolAspirisineDelgesicEgicalmFlectadolLaspalLysalQuinvetSolpirinVenopirinVetalgina
Other names
aspirin DL-lysineaspirin lysine saltDL-lysine acetylsalicylateDL-lysine monoacetylsalicylatelysine acetylsalicylatelysine monoacetylsalicylate
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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