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LZM008
- Development stage
- Unknown
- Lead developer
- Livzon Monoclonal Antibody
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous, Subcutaneous
01
Overview
LZM008 is a biosimilar tocilizumab developed by Livzon Mabpharm. It is a recombinant humanized monoclonal antibody that targets the interleukin-6 receptor (IL-6R), functioning as an IL-6 receptor antagonist. Tocilizumab and its biosimilars are primarily used as immunosuppressive agents in the treatment of autoimmune diseases such as rheumatoid arthritis. Clinical studies have demonstrated that LZM008 has pharmacokinetic equivalence, similar safety, and immunogenicity profiles compared to the reference product Actemra (tocilizumab). The drug has been registered for use in rheumatoid arthritis in China[1][2][3][5].
- Other names
- Recombinant humanized anti-human IL-6R monoclonal antibody solution for injection - Livzon Mabpharm
02
Targets
IL-6R (Interleukin-6 receptor subunit alpha)
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