Drug intelligence / Profile preview

M-267

Development stage
Preclinical
Lead developer
Johnson & Johnson
Modality
Small Molecules
01

Overview

M-267 is a **CD38 inhibitor** developed by Momenta Pharmaceuticals. Its mechanism of action is the inhibition of **CD38**, an ectoenzyme involved in the metabolism of NAD+ and calcium signaling, which plays a critical role in immune regulation and is a validated target in certain hematologic malignancies such as multiple myeloma. As of the latest available information, M-267 remains in preclinical development[2].

02

Targets

CD38 (Cluster of Differentiation 38)

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